Friday, March 9, 2012

5.19 - Mammal Cloning




sheep 1 = Original --genetically identical to clone--> dolly 


- need to obtain genetic info from 1. - done by removing a diploid cell (has a full set of genetic information) 
- at the same time - need to obtain a cell that has a tendency to divide 
sheep 2. completely different animal - has been treated with hormones to produce eggs 
- egg cell - tends to divide 
- do not want the genetic information of the egg and so it is removed (enucleated) 


- take the cell with the genetic information (want to copy) and the cell from the egg which wants to divide and FUSE them together 
- when fusing them together we have the genetic information and a cell that wants to divide 
- the combination of the two results in many cell divisions (like mitosis) to form a ball of cells (blastula - embryonic sheep - genetically identical to sheep 1) 


-embryo (blastula) of sheep 1 is placed into another sheep 3 - which is the surrogate mother 
- the embryo will grow into a fetus 
- this fetus is the clone of sheep 1 and is what we call dolly - it is genetically identical to sheep 1 
- this means they are a clone, even though their age is very different 





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